Wholesale Lion's Mane Mushrooms
Wholesale Lion's Mane Mushroom's (Hericium Erinaceus) are very nutritious and are rich in vitamins such as thiamine, riboflavin, and niacin. It's also a good source of essential minerals such as manganese, zinc, and potassium. Research shows that lion's mane has many health-promoting ingredients that come with several benefits.
Also known as Mountain-Priest mushroom, Bearded Tooth fungus, or Hou Tou Gu in traditional Chinese medicine (TCM), has a thick, shaggy appearance, like that of a lion’s mane, and grows on hardwood trees. Its color changes over time, from snow-white to creamy-white, to yellow, then to brown.
Potential Health Benefits of Lion's Mane Mushrooms
Research has found that lion's mane may protect against dementia*, reduce mild symptoms of anxiety and depression* and help repair nerve damage*. It also has strong anti-inflammatory, antioxidant and immune-boosting abilities and been shown to lower the risk of heart disease, cancer, ulcers and diabetes in animals*.
Research conducted to understand the antioxidant qualities of several types of mushrooms found that lion’s mane mushrooms show the fourth most potent antioxidant activity. Many health conditions such as heart diseases and autoimmune disorders such as arthritis are due to chronic inflammation. Bulk Lion’s mane mushrooms are rich in a specific type of carbohydrate called oligosaccharides that have many critical biological functions including antioxidative and antitumor activities.*
Easily customized for CBD product applications.
Our Bulk Lion's Mane extract products do not contain CBD or other hemp-derived cannabinoids, but can be blended with 20% concentration CBD water soluble powder or 10% concentration Full Spectrum water soluble powder as a custom order. Contact your Account Manager for a custom order quote.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. As with all dietary supplements, talk to your doctor before adding to your diet if you are pregnant, nursing or have a medical condition for which you are taking any prescription medications.
Frequently Asked Questions About Wholesale Lion's Mane Mushroom's
Is Lion's Mane mushroom extract the same as Lion's Mane mushroom powder?
Not really. A mushroom extract powder contains potent phytonutrients derived from a careful CO2 extraction process and then freeze dried to lock in the goodness. This freeze dried material is then ground and sifted to a nutriceutical grade product for formulation of premium products. Most often products labeled "mushroom powder" are the material that is left over after the extraction process. These may still contain some natural nutrients and they are typically less expensive than mushroom extract powders, but significantly less potent in high value compounds. Buyer beware.
Are Lion's Mane mushrooms psychoactive?
No, mushrooms that can cause a high contain compounds such as muscinol or psilocybin, a naturally occurring psychedelic that can alter your state of mind. As lion's mane does not contain psilocybin or other psychoactive compounds, there is no risk of you getting high from consuming the fungus.
Are there negative side effects of Lion's Mane mushrooms?
When eaten fresh or in dried form, Lion's Mane mushrooms are generally well tolerated. Reported side effects from some users include abdominal discomfort, nausea, and skin rash. It may also interact with blood-clotting medications (such as warfarin) and diabetes treatments. Talk with your doctor before use if you are pregnant, nursing or have a medical condition and are taking any prescription medications.
Is it safe to take Lion's Mane supplements daily?
It is considered safe and highly beneficial to take lion's mane mushrooms every day. Long-term benefits of lion's mane—such as their ability to prevent diabetes and alleviate symptoms of Parkinson's disease—become more pronounced the longer you use this mushroom.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing or have a medical condition for which you are are taking any prescription medications.
Clinical Research References
Lion's Mane mushrooms may protect against dementia*
- Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia | Int J Med Mushrooms 2013;15(6):539-54
- Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice | Biomed Res 2011 Feb;32(1):67-72
- Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice | J Biomed Sci 2016 Jun 27;23(1):49
- The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model | Int J Mol Sci. 2016 Nov; 17(11): 1810
- High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity | BMC Complement Altern Med. 2016; 16: 170
- Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial | Phytother Res. 2009 Mar;23(3):367-72
Lion's Mane mushrooms may help relieve mild symptoms of depression and anxiety*
- Effects of amycenone on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration | Pharmacol Biochem Behav 2015 Sep;136:7-12
- Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice | Int J Mol Sci 2018 Jan 24;19(2):341
- Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain | J Med Food 2018 Feb;21(2):174-180
- Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice | Evid Based Complement Alternat Med. 2017; 2017: 3864340
- Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake | JStage 2010 Volume 31 Issue 4 Pages 231-237
Lion's Mane mushrooms may help protect against ulcers in the digestive tract*
- Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals | Appl Microbiol Biotechnol 2014 Sep;98(18):7661-70
- Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) | Int J Med Mushrooms 2015;17(11):1055-60
- Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus | J Ethnopharmacol 2016 May 13;183:54-58
- In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion's Mane mushroom, Hericium erinaceus (higher Basidiomycetes) | Int J Med Mushrooms 2013;15(2):165-74
- Gastroprotective Effects of Lion's Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats | Evid Based Complement Alternat Med 2013;2013:492976
- Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis | Int J Med Mushrooms 2016;18(3):227-34
- Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota | Oncotarget 2017 Sep 6;8(49):85838-85857
- Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota | J Nutr Biochem 2018 Jul;57:67-76
- Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study | PLoS One 2016 Mar 2;11(3):e0150191
Lion's Mane mushrooms may help reduce the risk of heart disease*
- Hypolipidaemic Effect of Hericium erinaceum Grown in Artemisia capillaris on Obese Rats | Mycobiology. 2013 Jun; 41(2): 94–99
- Yamabushitake mushroom (Hericium erinaceus) improved lipid metabolism in mice fed a high-fat diet | Biosci Biotechnol Biochem 2010;74(7):1447-51
- Inhibitory effect on in vitro LDL oxidation and HMG Co-A reductase activity of the liquid-liquid partitioned fractions of Hericium erinaceus (Bull.) Persoon (lion's mane mushroom) | Biomed Res Int 2014;2014:828149
- Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation | Phytomedicine 2010 Dec 1;17(14):1082-5
Lion's Mane mushrooms may help manage diabetes symptoms*
- Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion's Mane) mushroom: A review | Int J Biol Macromol 2017 Apr;97:228-237
- Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats | BMC Complement Altern Med. 2013; 13: 253
- Antidiabetic and antioxidant activities of eight medicinal mushroom species from China | Int J Med Mushrooms 2015;17(2):129-40
Lion's Mane mushrooms may help fight and prevent cancer*
- A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium erinaceum | J Biomed Biotechnol. 2010; 2010: 716515
- A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment | Bioorg Med Chem Lett 2015 Dec 15;25(24):5712-5
- Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells | Food Funct 2011 Jun;2(6):348-56
- Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers | J Ethnopharmacol 2014 Apr 28;153(2):521-30
- Isolation and identification of aromatic compounds in Lion's Mane Mushroom and their anticancer activities | Food Chem 2015 Mar 1;170:336-42
- Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes | Cancer Lett 2005 Mar 18;220(1):21-8
- Hericium erinaceus (Lion's Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice | J Agric Food Chem 2013 May 22;61(20):4898-904
- Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers | J Ethnopharmacol 2014 Apr 28;153(2):521-30
Lion's Mane mushrooms may help reduce inflammation and oxidative stress*
- The inflammation theory of disease | EMBO Rep. 2012 Nov; 13(11): 968–970
- Composition and antioxidant activity of water-soluble oligosaccharides from Hericium erinaceus | Mol Med Rep 2015 May;11(5):3794-9
- Evaluation of Selected Culinary-Medicinal Mushrooms for Antioxidant and ACE Inhibitory Activities | Evid Based Complement Alternat Med 2012;2012:464238
- Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine | Int J Mol Sci. 2014 Sep; 15(9): 15073–15089
- Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis | Int J Med Mushrooms 2016;18(3):227-34
- Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides | Int J Biol Macromol 2013 Jan;52:66-71
- Protective Effect of Hericium erinaceus on Alcohol Induced Hepatotoxicity in Mice | Evid Based Complement Alternat Med 2015;2015:418023
- The Anti-Inflammatory Effects of Lion's Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages | Int J Med Mushrooms 2015;17(7):609-18
Lion's Mane mushrooms may support immune system health*
- Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology | Food Funct 2017 Mar 22;8(3):1020-1027
- Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota | Front Immunol 2017 Jun 12;8:666
- Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-Induced liver damage and mortality by stimulation of innate immune cells | J Agric Food Chem 2012 Jun 6;60(22):5590-6