March 14, 2025
Crafting the Perfect Formula to Alleviate Pain and Cramps for Women: A CBD, CBG, and Nutraceutical Super Stack
For countless women, pain and cramps—whether from menstrual cycles, chronic conditions like endometriosis, or everyday muscle tension—are a recurring challenge. While over-the-counter medications offer temporary relief, they often come with side effects or fail to address the root causes. Enter the world of natural remedies: cannabinoids like CBD (cannabidiol) and CBG (cannabigerol), paired with a powerhouse stack of nutraceuticals, could be the game-changer women have been waiting for. In this article, we’ll design a cutting-edge formula that blends science, nature, and innovation to ease pain and cramps holistically, delivered conveniently in capsules or gummies.

The Foundation: CBD and CBG
Cannabinoids, derived from the hemp plant, have taken the wellness world by storm—and for good reason. CBD is celebrated for its anti-inflammatory, analgesic (pain-relieving), and muscle-relaxant properties. Studies suggest it interacts with the endocannabinoid system (ECS) to regulate pain perception and reduce inflammation, making it a natural ally for menstrual cramps or chronic pain conditions.
CBG, often called the “mother of all cannabinoids,” complements CBD beautifully. Though less studied, emerging research highlights its potential as a muscle relaxant and anti-inflammatory agent. It may also inhibit the uptake of GABA (a neurotransmitter), promoting relaxation and reducing the intensity of cramps. Together, CBD and CBG form a dynamic duo that tackles both the symptoms and underlying drivers of pain.
Dosage Suggestion: 25–50 mg of CBD and 10–20 mg of CBG daily, adjusted based on individual tolerance and severity of symptoms.
The Super Stack: Eight Nutraceuticals to Amplify Relief
To elevate this formula, we’re stacking CBD and CBG with eight nutraceuticals known for their pain-relieving, anti-inflammatory, and hormone-balancing effects. Here’s the lineup:
- Magnesium (200–400 mg)
Often dubbed the “relaxation mineral,” magnesium is a must-have for cramp relief. It supports muscle relaxation, reduces prostaglandin levels (compounds that trigger uterine contractions), and eases tension. Studies show magnesium supplementation can significantly reduce menstrual pain intensity. - Turmeric (Curcumin, 500–1000 mg)
Curcumin, the active compound in turmeric, is a potent anti-inflammatory and antioxidant. It inhibits COX-2 enzymes (similar to ibuprofen) to dull pain and swelling, making it ideal for period-related inflammation or joint discomfort. - Ginger (500–1000 mg)
A traditional remedy for nausea and pain, ginger’s anti-inflammatory properties rival those of NSAIDs. Research suggests it can reduce menstrual pain as effectively as ibuprofen, with the added bonus of soothing an upset stomach—a common PMS sidekick. - Omega-3 Fatty Acids (1000–2000 mg)
Found in fish oil or algae, omega-3s are anti-inflammatory superstars. They help balance prostaglandins, reducing the severity of cramps, and support overall cellular health. Studies link higher omega-3 intake with less menstrual discomfort. - Vitamin B6 (50–100 mg)
This vitamin plays a key role in neurotransmitter synthesis, helping to stabilize mood and reduce pain sensitivity. It’s particularly effective for PMS-related cramps and bloating when paired with magnesium. - Ashwagandha (300–600 mg)
An adaptogen, ashwagandha helps the body manage stress—a major amplifier of pain. It also has anti-inflammatory and muscle-relaxing properties, making it a versatile addition for women dealing with hormonal fluctuations. - White Willow Bark (400–800 mg)
Nature’s aspirin, white willow bark contains salicin, which converts to salicylic acid in the body. It’s been used for centuries to relieve pain and inflammation, offering a gentler alternative to synthetic painkillers. - Cramp Bark (Viburnum opulus, 300–500 mg)
True to its name, cramp bark is a herbal gem for uterine spasms. It acts as a natural antispasmodic, relaxing smooth muscles and easing menstrual cramps with a targeted approach.
Bonus Boosters: Rounding Out the Formula
To supercharge this stack, consider these optional enhancers:
- Black Pepper Extract (Piperine, 5–10 mg): Boosts bioavailability of curcumin and other compounds.
- Chasteberry (Vitex agnus-castus, 200–400 mg): Balances hormones, reducing PMS symptoms and cycle-related pain.
How It Works: The Synergy
This formula isn’t just a random mix—it’s a symphony of complementary effects. CBD and CBG calm the nervous system and reduce inflammation at a cellular level. Magnesium, cramp bark, and white willow bark target muscle spasms and pain directly. Turmeric, ginger, and omega-3s tackle systemic inflammation, while ashwagandha and vitamin B6 support emotional resilience and hormonal harmony. Together, they address pain from multiple angles: inflammation, muscle tension, and stress.
Delivery Method
For convenience and optimal absorption, this formula is delivered as:
- Capsules: A daily blend of powdered nutraceuticals combined with CBD and CBG oil, encapsulated for precise dosing and easy swallowing.
- Gummies: A tasty, chewable option infused with CBD, CBG, and the nutraceutical stack, perfect for those who prefer a flavorful experience with consistent potency.
Timing and Use
Take the capsules or gummies daily for preventative benefits, with an extra dose 1–2 days before and during peak cramp periods. Capsules offer a quick, no-fuss option, while gummies provide a pleasant, gradual release—choose based on your lifestyle.
Safety and Considerations
While these ingredients are generally well-tolerated, individual responses vary. Start with lower doses to assess tolerance, especially with CBD and CBG. Avoid white willow bark if allergic to aspirin, and consult a doctor if pregnant, breastfeeding, or on medications like blood thinners.
The Future of Pain Relief
This CBD-CBG-nutraceutical stack, delivered in capsules or gummies, represents a bold step toward natural, holistic pain management for women. It’s customizable, science-informed, and rooted in nature’s best offerings. Imagine a world where cramps don’t dictate your day—this formula could be the key.
Ready to Produce This Next Level Menstrual Cramp Relief Supplement?
Choose Green Star Labs, a 50,000 sq ft cGMP-compliant, NSF-certified, and OTC-registered facility in San Diego, excels in crafting gummies, capsules, tinctures, and more. With flexible MOQs, a cost-plus model, and custom terms, we can formulate this blend. Covalent manufactures all orders here, ensuring quality. Contact Rich Weisner at rich@covalentcbd.com or call 702-766-4367 to bring this supplement stack to market.

About Rich Weisner
I specialize in helping businesses create, formulate, and bring innovative products to market. With expertise in the development of custom CBD formulations, nutraceuticals, and functional mushrooms, I work closely with clients to craft high-quality products that meet their unique needs.
My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!
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