February 21, 2025
Introducing the 5 Knights of the Roundtable: Optimized Supplement Formulations for Pain Management, Energy, Sleep, Immune Support, and Skincare

As the demand for nutraceuticals continues to rise, innovative formulations are being developed to address specific needs across various health and wellness categories. From pain management to skincare, supplements are playing a more integral role in supporting overall health. The rise of different delivery formats — capsules, tablets, tinctures, topicals, and gummies — makes it easier than ever to find an effective supplement that fits your lifestyle and addresses your unique health needs.
In this article, we’ll explore five unique formulations tailored to specific health concerns and delivered through distinct mediums. We’ll dive into the benefits of each, as well as the market growth projections for each area, demonstrating why these products should be on your radar.
#1. Pain Management Formula – Capsules
Ingredients:
- Turmeric (Curcumin) – Known for its anti-inflammatory properties, turmeric is a powerhouse for pain relief. Studies have shown it may reduce chronic pain and inflammation, particularly in conditions like arthritis.
- CBD – A non-psychoactive compound in cannabis that has shown to help reduce pain and inflammation.
- Boswellia – This herb has anti-inflammatory effects that help manage pain, especially in joints.
- Black Pepper Extract – Enhances the bioavailability of turmeric and CBD for faster and more effective absorption.
- Ginger – Acts as a natural pain reliever with anti-inflammatory effects.
Why Capsules?
Capsules are an excellent choice for pain management formulas as they provide a precise, measured dosage, ensuring consistent results for pain relief. The capsule format is easy to swallow, and with a highly potent formula, it’s perfect for people seeking convenience and high bioavailability.
Market Growth
The global pain management market is projected to reach $83.8 billion by 2026, growing at a CAGR of 5.6%. With an aging population and an increase in chronic pain conditions, pain relief products like these are highly in demand.
#2. Energy Formula – Tablets
Ingredients:
- Caffeine – A well-known stimulant that increases alertness and reduces fatigue.
- L-Theanine – Works synergistically with caffeine to promote calmness without sedation, boosting focus and mental clarity.
- Rhodiola Rosea – An adaptogen known for its ability to combat fatigue and improve physical and mental performance.
- Vitamin B12 – A crucial nutrient for energy production and maintaining healthy brain function.
- Ginseng – Known for its ability to enhance physical performance and fight fatigue.
Why Tablets?
Tablets are perfect for energy formulas because they allow for precise dosing and are convenient for people on the go. Tablets can also carry multiple active ingredients, ensuring the formulation is balanced and effective. The compact form makes it easy to take when needed most, such as during the mid-afternoon slump.
Market Growth
The global energy supplements market is expected to grow from $10.9 billion in 2021 to $16.7 billion by 2028, with a CAGR of 6.2%. With the growing demand for natural energy boosters, the popularity of energy tablets is on the rise.
#3. Immune Support Formula – Gummies
Ingredients:
- Vitamin C – A powerful antioxidant that supports the immune system by stimulating the production of white blood cells.
- Elderberry Extract – Known for its immune-boosting properties, elderberry has been used for centuries to fight infections.
- Zinc – Plays a key role in immune function by helping the body’s immune cells perform their tasks more effectively.
- Echinacea – Widely used to reduce the severity and duration of colds.
Turmeric – A natural anti-inflammatory that supports the immune system and helps the body ward off illness.
Why Gummies?
Gummies offer a fun and effective delivery method for immune support formulas. They are not only convenient but also offer enhanced bioavailability compared to pills. The chewy texture and sweet taste are perfect for people who want to take their daily supplements without hassle, especially kids or adults who may have difficulty swallowing pills.
Market Growth
The global immune health supplements market is expected to grow from $18.3 billion in 2021 to $38.3 billion by 2030, with a CAGR of 8.4%. The increasing focus on preventative health has driven the demand for immune support products.
#4. Sleep Support Formula – Topicals
Ingredients:
- Melatonin – A naturally occurring hormone that helps regulate sleep-wake cycles, making it ideal for those suffering from insomnia or jet lag.
- Chamomile Extract – Known for its calming effects, chamomile promotes relaxation and supports sleep.
- CBD – Often used to help reduce anxiety and pain, allowing for better sleep quality.
- Lavender Extract – A well-known herb for its relaxing properties, perfect for easing tension and promoting restful sleep.
- Passionflower – Known to help with anxiety reduction and improve sleep quality.
Why Topicals?
Topicals are perfect for localized applications, especially for sleep products that aim to calm and relax muscles before sleep. Creams or lotions containing calming herbs and CBD can be applied to the skin, helping the body relax and prepare for a good night’s rest. They also provide a calming, ritualistic experience before bed.
Market Growth
The sleep aids market is projected to reach $104.25 billion by 2030, driven by growing consumer awareness of the importance of sleep and natural sleep remedies.
#5. Skincare Formula – Powdered Drink Mixes
Ingredients:
- Hyaluronic Acid – Known for its ability to hydrate and plump the skin, it helps reduce the appearance of fine lines and wrinkles.
- Collagen – Vital for skin elasticity, collagen supplements can help improve skin texture and prevent sagging.
- Vitamin E – An antioxidant that helps repair damaged skin and improves the skin’s texture and tone.
- Biotin – Essential for skin health, biotin promotes healthy cell growth and reduces dryness.
- Aloe Vera – Helps soothe the skin, reducing redness and inflammation while promoting healing.
Why Powdered Drink Mixes?
Powdered drink mixes are an excellent choice for skincare formulas because they are easy to mix into water or other beverages, making them perfect for on-the-go lifestyles. These mixes are a convenient way to ensure you’re getting a daily dose of vital skincare ingredients, hydrating your body while working from the inside out.
Market Growth
The global skincare supplements market is projected to grow from $6.5 billion in 2021 to $13.5 billion by 2030, driven by increasing demand for natural and preventative skincare solutions.
The Bottom Line Each of these formulations—whether for pain management, energy, sleep, immune support, or skincare—addresses significant consumer needs and can be effectively delivered through different mediums. With the rise in demand for natural and holistic health solutions, supplements are poised to play a major role in the future of wellness. By creating products that combine powerful ingredients in convenient formats, brands can tap into fast-growing markets and offer consumers effective, science-backed solutions.
How Covalent Can Help
At Covalent, we specialize in formulating and manufacturing high-quality cannabinoid and nutraceutical products, offering full-service solutions to bring your product ideas to market. With our cGMP-compliant manufacturing process and low minimum order quantities (MOQs), we help businesses of all sizes create effective and impactful products. Whether you’re looking to create gummies, capsules, tinctures, or topicals, we’re here to help you bring your vision to life.
Ready to launch your next big product?
Contact us today to learn more about our capabilities and how we can help you create the perfect formula!

About Rich Weisner
I specialize in helping businesses create, formulate, and bring innovative products to market. With expertise in the development of custom CBD formulations, nutraceuticals, and functional mushrooms, I work closely with clients to craft high-quality products that meet their unique needs.
My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!
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