January 5, 2025
The Top 5 Supplements for Cognitive Boost and How to Maximize Their Nootropic Benefits
The nootropics market is experiencing exponential growth as consumers seek effective ways to enhance focus, memory, and mental clarity. These five supplements stand out for their proven cognitive benefits, synergistic combinations, and adaptability across various formats.

#1. Lion’s Mane Mushroom
Cognitive Benefits:
Stimulates nerve growth factor (NGF), supporting brain cell repair and growth.
Improves memory and cognitive function. (Source: Journal of Translational Medicine)
Complementary Supplements:
Choline: Boosts acetylcholine production for enhanced memory.
Bacopa Monnieri: Reduces oxidative stress for better brain function.
Best Mediums:
Powders: Ideal for coffee or smoothies.
Capsules: Convenient for daily supplementation.
Market Insights:
Target Audience: Wellness enthusiasts, biohackers, and students.
Growth: The functional mushroom market is projected to grow at a CAGR of 8.1%, reaching $24 billion by 2032.
#2. Alpha-GPC
Cognitive Benefits:
- Increases acetylcholine levels, critical for learning and memory.
- Supports brain recovery and neuroprotection. (Source: Frontiers in Aging Neuroscience)
Complementary Supplements:
- L-Theanine: Promotes calm focus.
- Caffeine: Synergizes with Alpha-GPC for enhanced alertness.
Best Mediums:
- Capsules: Ensures accurate dosing.
- Beverages: Functional energy drinks with added nootropics.
Market Insights:
- Target Audience: Gamers, professionals, and athletes.
- Growth: The nootropics market is estimated to grow at a CAGR of 14.2%, exceeding $10 billion by 2030.
#3. Bacopa Monnieri
Cognitive Benefits:
- Enhances memory retention and recall.
- Reduces anxiety and improves focus. (Source: Phytomedicine)
Complementary Supplements:
- Ashwagandha: Combats stress for improved mental clarity.
- Ginkgo Biloba: Improves blood flow to the brain.
Best Mediums:
- Tinctures: High bioavailability and fast absorption.
- Gummies: Appeals to younger audiences.
Market Insights:
- Target Audience: Older adults and students.
- Growth: The herbal supplement market is growing at a CAGR of 6.8%.
#4. Omega-3 Fatty Acids (DHA/EPA)
Cognitive Benefits:
- Supports brain structure and function.
- Improves mood and reduces cognitive decline. (Source: Nature Reviews Neuroscience)
Complementary Supplements:
- Curcumin: Enhances anti-inflammatory effects.
- Vitamin D: Synergistic for brain health and mood.
Best Mediums:
- Softgels: Standard delivery for omega-3 oils.
- Emulsions: Enhanced bioavailability.
Market Insights:
- Target Audience: Seniors, parents, and wellness enthusiasts.
- Growth: The omega-3 market is set to grow at a CAGR of 7.4%, reaching $8.5 billion by 2027.
#5. Rhodiola Rosea
Cognitive Benefits:
- Boosts energy and reduces mental fatigue.
- Improves memory and concentration. (Source: Planta Medica)
Complementary Supplements:
- Panax Ginseng: Amplifies energy-boosting properties.
- CoQ10: Enhances mitochondrial energy production.
Best Mediums:
- Capsules: Reliable for daily supplementation.
- Shots: Convenient for quick energy boosts.
Market Insights:
- Target Audience: Athletes, professionals, and students.
- Growth: The adaptogen market is growing at a CAGR of 6.1%, reaching $3.8 billion by 2030.
Strategies for Nootropic Sales Success
1. Formulation and Bioavailability
- Use liposomal delivery systems for fat-soluble ingredients like Omega-3 and curcumin.
- Consider water-soluble powders for instant absorption in beverages.
2. Targeted Marketing
- Focus on students and professionals for memory and focus blends.
- Appeal to aging populations with supplements that prevent cognitive decline.
3. Trends and Opportunities
- Personalization: DNA-based nootropic solutions.
- Functional Foods: Combine nootropics with snacks and drinks.
How Covalent Can Help
At Covalent, we specialize in creating cutting-edge, high-bioavailability formulations to help businesses thrive in the competitive nootropics market. With cGMP-compliance, NSF certification, and OTC licensing, we’re your partner in launching premium products. Let’s work together to make your vision a reality.

About Rich Weisner
I specialize in helping businesses create, formulate, and bring innovative products to market. With expertise in the development of custom CBD formulations, nutraceuticals, and functional mushrooms, I work closely with clients to craft high-quality products that meet their unique needs.
My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!
Recent Posts
- February 8, 2025 – Cannabinoids in Skincare: A Natural Revolution in Beauty and Wellness
- February 7, 2025 – CBDA & CBGA: The Shining Stars of the Cannabinoid World
- February 6, 2025 – Succeeding in the CBD Business: Leveraging Rare Cannabinoids and Nutraceuticals to Elevate Your Brand
- February 5, 2025 – The Nutritional Power of Oysters and How to Harness It in Supplements
- February 4, 2025 – 5 Brain Health Supplements Off the Radar That Should Be in Your Gummy Formulation
- January 31, 2025 – Checkmate in Health: The Powerful Pairing of Black Pepper and Turmeric – A Winning Move for Pain Relief and Immunity!
- January 30, 2025 – The Power of Ginger: A Super Supplement for Health and Wellness
- January 28, 2025 – The Benefits of Ursolic Acid for Men Over 40: A Key to Prostate Health
- January 27, 2025 – Top 5 Nutraceutical Ingredients To Keep On Your Radar In 2025
- January 24, 2025 – Collagen + Colostrum: The Powerhouse Duo for Skin, Hair, Teeth, and Nails
- January 22, 2025 – Anti-Aging Supplements: The Market, Trends, and Why Now is the Time to Start Your Product
- January 21, 2025 – An Amazing New Product Launch: High Potency Functional Mushroom Shots by Covalent
- January 17, 2025 – The Link Between Vitamin D Deficiency and Alzheimer’s Disease: How Covalent Can Help with Effective Formulations
- January 16, 2025 – The Perfect THCV Weight Loss and Energy Formula: The Power of THCV, CBC, and Complementary Nutraceuticals
- January 10, 2025 – The Rise of OTC Cosmetics: Top Products and Ingredients Driving Market Growth
- January 9, 2025 – Fueling Success with NSF Sport-Certified Products: How Covalent Can Elevate Your Brand
- January 8, 2025 – How to Detox from Everyday Toxins and the Top 5 Supplements to Help You Do It
- January 7, 2025 – The Blossoming Cannabinoid and Nutraceutical Beverage Industry: A Comprehensive Guide to Growth and Opportunity
- January 6, 2025 – Elevate Your Tinctures with Oil-Soluble Nutraceuticals for Cognitive and Immune Support
- January 3, 2025 – The Top 5 Supplements Small Businesses Should Be Making Right Now – And How Covalent Can Help You Succeed