February 13, 2025
Trust Your Gut: The Power of Gut Health and Supplements
Digestive health is vital to overall wellness, and as the world turns its attention to gut health, the demand for gastrointestinal supplements is on the rise. A healthy gut influences everything from immunity to mood, making it essential to support digestive health. The global gastrointestinal health supplement market is growing rapidly, driven by an increasing awareness of the importance of gut health. In fact, according to Grand View Research, the gastrointestinal health market is expected to reach $14.98 billion by 2027, growing at a CAGR of 5.8%.

So, what are the best ingredients to incorporate into your gastrointestinal supplements to ensure maximum benefit?
Here are some of the top supplements and formulations that can support gut health:
#1. Probiotics
- What It Does: Probiotics are live beneficial bacteria that support a healthy balance in the gut, improving digestion and promoting a robust immune system.
- Benefits: Probiotics can reduce symptoms of irritable bowel syndrome (IBS), promote gut flora balance, and improve digestion.
- Clinical Studies: Research published in the World Journal of Gastroenterology shows that probiotics can be effective in managing IBS, improving gut function, and alleviating constipation and bloating.
- Formulation Ideas: Gummies or capsules are excellent choices for probiotic supplementation.
#2. Digestive Enzymes
- What It Does: Digestive enzymes help break down food into nutrients your body can absorb, reducing bloating, indigestion, and discomfort.
- Benefits: Supplementing with digestive enzymes can reduce discomfort from indigestion, bloating, and heartburn, and it may enhance nutrient absorption.
- Clinical Studies: A study published in the American Journal of Clinical Nutrition found that digestive enzyme supplementation improved digestion and reduced bloating.
- Formulation Ideas: Capsules or soft gels are ideal for digestive enzymes, as they are stable and effective in delivering the enzymes to the digestive tract.
#3. L-Glutamine
- What It Does: L-glutamine is an amino acid that plays a key role in maintaining the integrity of the intestinal lining, which is crucial for preventing leaky gut.
- Benefits: L-glutamine supplementation supports gut barrier function, reduces inflammation, and aids in repairing the intestinal wall, helping those with inflammatory bowel diseases like Crohn’s disease or colitis.
- Clinical Studies: A clinical study published in the Journal of Clinical Gastroenterology demonstrated the positive effects of L-glutamine supplementation in reducing intestinal permeability and improving gut function.
- Formulation Ideas: L-glutamine works well in powder or capsule form.
#4. Fiber (e.g., Psyllium Husk)
- What It Does: Fiber is a crucial part of digestive health, as it helps regulate bowel movements, reduces constipation, and promotes healthy gut flora.
- Benefits: Fiber helps regulate digestion and is effective in alleviating both constipation and diarrhea. It also plays a key role in managing weight and reducing cholesterol.
- Clinical Studies: A study published in the American Journal of Clinical Nutrition showed that dietary fiber improves digestive health, aids in weight management, and lowers cholesterol levels.
- Formulation Ideas: Fiber is commonly found in gummies, capsules, and powders.
#5. Ginger Root
- What It Does: Ginger has been used for centuries to relieve nausea, improve digestion, and reduce bloating.
- Benefits: Ginger is known to stimulate digestive enzymes, reducing nausea and promoting overall digestive comfort. It can also ease symptoms of indigestion and bloating.
- Clinical Studies: A study published in Food & Function concluded that ginger supplementation significantly improved gastric motility and alleviated nausea and bloating.
- Formulation Ideas: Gummies and soft gels are ideal for ginger supplementation.
Why Formulations Matter
As the gut health market continues to grow, there’s a significant demand for convenient and effective supplement formats that can deliver these digestive benefits. Gummies are especially popular because they are easy to consume and offer a pleasant, enjoyable experience while delivering essential ingredients like probiotics, digestive enzymes, and fiber. Capsules and soft gels are also a great option for those who prefer a more traditional supplement format, while powders can offer flexibility and higher doses for those needing extra support.
At Covalent, we specialize in creating custom formulations to meet the growing demand for digestive health supplements. Whether you’re looking to develop a gummy, capsule, tincture, or beverage, we work with you every step of the way—from formulation to packaging—ensuring you meet the highest standards of quality with our cGMP-compliant facility.
Digestive Health Supplement Market Trends
The digestive health supplement market is witnessing significant growth due to increased awareness about gut health, the rise in digestive disorders, and the growing popularity of natural and functional foods. With gut health influencing everything from immune function to mood, more consumers are turning to supplements to promote a healthy digestive system. As a result, the demand for innovative, high-quality digestive health products is stronger than ever.
How Covalent Can Help
At Covalent, we understand the importance of formulating products that not only meet the needs of consumers but also stand out in an increasingly competitive market. With our low MOQ options and GMP-compliant manufacturing, we help businesses quickly and efficiently bring effective digestive health supplements to market.
If you’re ready to develop your own gastrointestinal products and tap into the growing market for digestive health, Covalent is here to help you every step of the way. From custom formulations to expert advice on ingredient selection, we’ve got you covered.
Ready to start creating your next big product? Register your account and request a quote today!

About Rich Weisner
I specialize in helping businesses create, formulate, and bring innovative products to market. With expertise in the development of custom CBD formulations, nutraceuticals, and functional mushrooms, I work closely with clients to craft high-quality products that meet their unique needs.
My goal is to help businesses scale and succeed by offering personalized support, industry knowledge, and access to cutting-edge manufacturing technology. Let’s connect and explore how we can collaborate to bring your product ideas to life!
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